Safe at home: a novel

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    Safe at Home by Mike Lupica Reviews, Discussion, Bookclubs

    Motivations Current cell engineering efforts, despite the numerous notable successes, are fundamentally hampered by the complexity of biological systems which makes it nearly impossible to perform truly rational systems design. The analytic arsenal of systems biology has tremendously advanced our ability to deduce interactions in cells. However, this knowledge still has to be translated into our ability to reliably construct systems capable of performing novel synthetic tasks (as opposed to doing naturally present syntheses better) and designing systems beyond the current part-by-part engineering. Here, biological engineering faces a fundamental obstacle.

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